Description

2-(5,7-Dioxo-5,7-Dihydro-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)-3-Phenylpropanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial value for the development of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for use in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzymatic pathways.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical precursor in multi-step synthetic routes for complex, high-value APIs.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study specific biological mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(5,7-Dioxo-5,7-Dihydro-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)-3-Phenylpropanoic Acid
CAS No.	126346-96-1
Molecular Formula	C15H11N3O4
Molecular Weight	297.27 g/mol
Synonyms	6-[2-Carboxy-2-phenylethyl]-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione; 3-Phenyl-2-(5,7-dioxo-6H-pyrrolo[3,4-b]pyrazin-6-yl)propanoic acid; 2-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyrazin-6-yl)-3-phenylpropionic acid; Pyrrolopyrazinedione propanoic acid derivative; CAS 126346-96-1
EINECS	Contact for details

Quality Control

Our 2-(5,7-Dioxo-5,7-Dihydro-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)-3-Phenylpropanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.