Description

1,4,8,11-Tetrakis(Ethoxycarbonylmethyl)-1,4,8,11-Tetraazacyclotetradecane is a functionalized macrocyclic tetraamine derivative, serving as a key intermediate for the synthesis of advanced chelating agents and metal complexes. This compound matters for its ability to form highly stable complexes with a variety of metal ions, which is critical for applications requiring precise metal coordination and sequestration. It is primarily needed by researchers and manufacturers in the fields of molecular imaging contrast agents, radiopharmaceuticals, catalysis, and advanced materials science.

Application

• Precursor for MRI Contrast Agents: Serves as a critical building block for synthesizing gadolinium(III) and other lanthanide-based complexes used in magnetic resonance imaging (MRI).
• Radiopharmaceutical Development: Used in the chelator design for radiolabeling with isotopes like 64Cu, 68Ga, and 177Lu for diagnostic and therapeutic applications.
• Catalyst Ligand Synthesis: Functionalized to create sophisticated ligands for homogeneous catalysis, including oxidation and polymerization reactions.
• Metal Scavenging & Separation: Employed in the development of selective resins or solutions for the removal or recovery of specific metal ions from industrial streams.
• Supramolecular Chemistry: Acts as a versatile scaffold for constructing molecular cages, sensors, and other functional supramolecular assemblies.
• Chemical Research Intermediate: Provides a versatile platform for organic and inorganic chemists to develop new macrocyclic compounds with tailored properties.

Basic Information

Product Name	1,4,8,11-Tetrakis(Ethoxycarbonylmethyl)-1,4,8,11-Tetraazacyclotetradecane
CAS No.	126320-57-8
Molecular Formula	C30H56N4O8
Molecular Weight	600.79 g/mol
Synonyms	1,4,8,11-Tetraazacyclotetradecane-1,4,8,11-tetraacetic acid tetraethyl ester; Tetraethyl 1,4,8,11-tetraazacyclotetradecane-1,4,8,11-tetraacetate; TETA tetraethyl ester; Cyclam tetraacetic acid tetraethyl ester; 1,4,8,11-Tetraazacyclotetradecane-1,4,8,11-tetraacetic acid, tetraethyl ester; Ethyl DO4A-tetraester; 1,4,8,11-Tetrakis(carbethoxymethyl)-1,4,8,11-tetraazacyclotetradecane
EINECS	Contact for details

Quality Control

Our 1,4,8,11-Tetrakis(Ethoxycarbonylmethyl)-1,4,8,11-Tetraazacyclotetradecane is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis, to ensure it meets exacting R&D and production standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.