Description

4-Nitro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine 1-Oxide is a specialized heterocyclic building block and key synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its unique fused-ring nitropyridine N-oxide structure, which provides a versatile scaffold for constructing complex molecules. This compound is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a key building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its N-oxide functionality.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and dyes.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	4-Nitro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine 1-Oxide
CAS No.	126259-73-2
Molecular Formula	C8H8N2O3
Molecular Weight	180.16 g/mol
Synonyms	4-Nitro-6,7-dihydro-5H-cyclopenta[b]pyridine 1-oxide; 4-Nitro-5H-cyclopenta[b]pyridine 1-oxide; 4-Nitro-6,7-dihydro-5H-cyclopenta[b]pyridine N-oxide; 4-Nitro-5H-cyclopenta[2,1-b]pyridine 1-oxide; Cyclopenta[b]pyridine, 4-nitro-6,7-dihydro-5H-, 1-oxide; 126259-73-2 (CAS); 4-Nitro-6,7-dihydro-5H-cyclopenta[b]pyridine-1-oxide
EINECS	Contact for details

Quality Control

Our production of 4-Nitro-6,7-Dihydro-5H-Cyclopenta[B]Pyridine 1-Oxide adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to minimize oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.