Description

4-Acetyl-2,2-Difluoro-1,3-Benzodioxole is a specialized fluorinated organic building block characterized by its unique benzodioxole core and acetyl functionality. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and manufacturers in the fine chemical, pharmaceutical, and material science industries seeking to introduce difluoromethylene and acetyl motifs into target structures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluorobenzodioxole moiety can improve pesticidal activity and environmental profile.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers, coatings, and electronic materials with specific optical or dielectric properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for constructing complex ligands used in asymmetric catalysis and transition metal complexes.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and the behavior of fluorinated aromatic systems under various conditions.

Basic Information

Product Name	4-Acetyl-2,2-Difluoro-1,3-Benzodioxole
CAS No.	126120-83-0
Molecular Formula	C9H6F2O3
Molecular Weight	200.14 g/mol
Synonyms	2,2-Difluoro-4-acetyl-1,3-benzodioxole; 4-Acetyl-2,2-difluorobenzo[d][1,3]dioxole; 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)ethan-1-one; 4-Acetyl-2,2-difluorobenzodioxole; 2,2-Difluoro-4-acetylbenzo-1,3-dioxole
EINECS	Contact for details

Quality Control

Our 4-Acetyl-2,2-Difluoro-1,3-Benzodioxole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.