Description

1-[2,6-Dichloro-4-(Fluoromethyl)Phenyl]-3-(2-Methylpropyl)-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in specialized therapeutic areas. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors engaged in innovative synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, especially those targeting specific receptor pathways.
• Agrochemical Research: Used in the development and production of next-generation pesticides and herbicides, leveraging its pyrazole core structure.
• Chemical Synthesis: Serves as a versatile reagent for constructing complex heterocyclic compounds in medicinal chemistry.
• API Process Development: Employed in scale-up and optimization studies for the commercial manufacturing of active pharmaceutical ingredients.
• Life Science Research: Utilized in biochemical and pharmacological research as a tool compound for studying biological mechanisms.

Basic Information

Product Name	1-[2,6-Dichloro-4-(Fluoromethyl)Phenyl]-3-(2-Methylpropyl)-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester
CAS No.	126100-06-9
Molecular Formula	C17H19Cl2FN2O2
Molecular Weight	389.25 g/mol
Synonyms	Ethyl 1-[2,6-dichloro-4-(fluoromethyl)phenyl]-3-isobutyl-1H-pyrazole-5-carboxylate; 1H-Pyrazole-5-carboxylic acid, 1-[2,6-dichloro-4-(fluoromethyl)phenyl]-3-(2-methylpropyl)-, ethyl ester; 3-Isobutyl-1-[2,6-dichloro-4-(fluoromethyl)phenyl]-1H-pyrazole-5-carboxylic acid ethyl ester; CAS 126100-06-9
EINECS	Contact for details

Quality Control

Our production of 1-[2,6-Dichloro-4-(Fluoromethyl)Phenyl]-3-(2-Methylpropyl)-1H-Pyrazole-5-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities operating under cGMP (current Good Manufacturing Practice) guidelines where applicable. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.