Description

[(S)-Tol-Binap Rucl Benzene]Cl is a high-purity, chiral ruthenium complex widely recognized as a highly effective asymmetric hydrogenation catalyst. This compound matters for its ability to impart exceptional enantioselectivity and catalytic activity in the synthesis of chiral intermediates, which are critical for producing optically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries seeking to optimize stereoselective synthetic routes.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of functionalized olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Pharmaceutical Manufacturing: Key in the production of chiral active pharmaceutical ingredients (APIs) for cardiovascular, central nervous system, and anti-infective drugs.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the synthesis of specialty flavors, fragrances, and advanced material precursors with high optical purity.
• Academic & Industrial R&D: A valuable tool for method development and exploring new catalytic transformations in organic chemistry.
• Process Chemistry Optimization: Employed for scaling up efficient and sustainable catalytic processes from lab to pilot plant.

Basic Information

Product Name	[(S)-Tol-Binap Rucl Benzene]Cl
CAS No.	126085-10-7
Molecular Formula	C44H38ClP2Ru
Molecular Weight	778.22 g/mol
Synonyms	(S)-Tol-BINAP RuCl(benzene) Chloride; (S)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl Ruthenium (II) Chloride Benzene Complex; (S)-TolBINAP-RuCl(C6H6)Cl; (S)-RuCl2(p-cymene)(Tol-BINAP); (S)-Tol-BINAP Ru(II) Benzene Chloride Complex; (S)-DTB-RuCl(benzene)Cl; Ru-((S)-Tol-BINAP)Cl(benzene)Cl; (S)-BINAP-Ru Catalyst Derivative
EINECS	Contact for details

Quality Control

Our [(S)-Tol-Binap Rucl Benzene]Cl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (ee) of the ligand, and residual solvent content are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated area. Due to its sensitivity to light and oxidation, prolonged exposure to air or ambient conditions should be avoided to maintain catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (ee of Ligand)	≥ 98.0%
Ruthenium Content	12.5 - 13.5 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.