Description

4(1H)-Quinolinone, 3-Chloro-2-(Trifluoromethyl)- is a high-purity, halogenated quinolinone derivative serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its core value lies in its unique molecular scaffold, which is essential for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides due to its bioactive quinolinone core.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport or host materials in electronic displays and lighting.
• Coordination Chemistry & Ligand Design: Acts as a ligand or precursor for metal-organic frameworks (MOFs) and catalysts.
• Fluorinated Compound Research: Valuable for studying the effects of the trifluoromethyl group on molecular properties in medicinal and material chemistry.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized heterocyclic dyes.

Basic Information

Product Name	4(1H)-Quinolinone, 3-Chloro-2-(Trifluoromethyl)-
CAS No.	125647-90-7
Molecular Formula	C10H5ClF3NO
Molecular Weight	247.60 g/mol
Synonyms	3-Chloro-2-(trifluoromethyl)quinolin-4(1H)-one; 3-Chloro-2-(trifluoromethyl)-1H-quinolin-4-one; 3-Chloro-2-(trifluoromethyl)-4(1H)-quinolinone; 3-Chloro-2-trifluoromethyl-4-quinolone; 2-Trifluoromethyl-3-chloro-4-hydroxyquinoline; 3-Chloro-2-trifluoromethyl-4-hydroxyquinoline; 125647-90-7 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinolinone, 3-Chloro-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.