Description

4-Hydroxy-6-(trifluoromethoxy)-2-(trifluoromethyl)quinoline is a high-value, fluorinated quinoline derivative characterized by its unique trifluoromethoxy and trifluoromethyl substituents. This compound serves as a critical advanced intermediate in the synthesis of complex molecules, offering significant advantages in modulating the physicochemical properties of target compounds. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-infectives, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the creation of new pesticides and herbicides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Material Science Precursor: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to the electron-withdrawing nature of the fluorinated groups.
• Chemical Biology Probe: Serves as a scaffold for designing fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: An essential substrate for fine chemical manufacturers offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	4-Hydroxy-6-(Trifluoromethoxy)-2-(Trifluoromethyl)Quinoline
CAS No.	125647-79-2
Molecular Formula	C12H5F6NO2
Molecular Weight	309.17 g/mol
Synonyms	4-Hydroxy-6-(trifluoromethoxy)-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-6-(trifluoromethoxy)-4-quinolinol; 6-(Trifluoromethoxy)-2-(trifluoromethyl)quinolin-4-ol; 4-Quinolinol, 6-(trifluoromethoxy)-2-(trifluoromethyl)-; 4-Hydroxy-6-trifluoromethoxy-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-6-(trifluoromethoxy)-2-(trifluoromethyl)quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.