Description

2,3,5-Tri-o-Benzyl-L-Arabinofuranose is a key protected carbohydrate intermediate, specifically a fully benzylated derivative of L-arabinose. This compound is essential for its role as a versatile chiral building block in the stereoselective synthesis of complex nucleosides, nucleotides, and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral drugs, oligonucleotide therapeutics, and novel glycosylation methodologies.

Application

• Nucleoside/Nucleotide Synthesis: A critical precursor for the preparation of L-nucleoside analogs, which are investigated for their antiviral and anticancer properties.
• Oligonucleotide Chemistry: Serves as a protected sugar moiety in the solid-phase synthesis of oligonucleotides, particularly for creating modified backbones or sugar structures.
• Glycosylation Reactions: Used as a glycosyl donor or acceptor in the synthesis of complex oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: A high-value building block in the research and development (R&D) and process chemistry stages for new active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Employed in the synthesis of labeled or modified sugars for studying biological recognition and metabolic pathways.
• Chiral Catalyst/P ligand Synthesis: The scaffold can be used to develop novel chiral ligands for asymmetric catalysis.

Basic Information

Product Name	2,3,5-Tri-o-Benzyl-L-Arabinofuranose
CAS No.	125598-74-5
Molecular Formula	C26H28O5
Molecular Weight	420.50 g/mol
Synonyms	1,2,3-Tri-O-benzyl-α-L-arabinofuranose; L-Arabinofuranose, 1,2,3-tris-O-(phenylmethyl)-; 2,3,5-Tri-O-benzyl-L-arabinofuranose; 1,2,3-Tri-O-benzyl-L-arabinofuranose; Tri-O-benzyl-L-arabinofuranose; 2,3,5-Tris-O-benzyl-L-arabinofuranose; (2R,3S,4S,5R)-2,3,4-Tris(benzyloxy)-5-(hydroxymethyl)oxolane
EINECS	Contact for details

Quality Control

Our 2,3,5-Tri-o-Benzyl-L-Arabinofuranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.