Description

8-Bromo-4-Chloro-2-Phenylquinoline is a high-purity, multi-functional halogenated quinoline derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated quinoline motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research programs.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science Precursor: Serves as a starting material for creating organic light-emitting diodes (OLEDs), liquid crystals, and other functional organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Catalyst Ligand Synthesis: The halogen and nitrogen atoms provide handles for constructing complex ligands used in transition metal catalysis.
• Custom Synthesis & Scale-Up: Available for contract research organizations (CROs) and chemical manufacturers requiring reliable, high-quality intermediates for custom synthesis projects.

Basic Information

Product Name	8-Bromo-4-Chloro-2-Phenylquinoline
CAS No.	125443-61-0
Molecular Formula	C15H9BrClN
Molecular Weight	318.60 g/mol
Synonyms	2-Phenyl-8-bromo-4-chloroquinoline; 4-Chloro-8-bromo-2-phenylquinoline; 8-Bromo-4-chloro-2-phenyl-quinoline; Quinoline, 8-bromo-4-chloro-2-phenyl-; 125443-61-0; 8-Br-4-Cl-2-Ph-quinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloro-2-Phenylquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.