Description

8-Bromo-4-Chloroquinazoline is a high-purity halogenated quinazoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual reactive sites, which enable precise functionalization for creating complex molecular architectures. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in developing novel herbicides and fungicides with specific modes of action.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials and liquid crystals.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research and assay development.
• Academic & Contract Research: Essential for methodological studies in heterocyclic and medicinal chemistry within R&D laboratories.

Basic Information

Item	Detail
Product Name	8-Bromo-4-Chloroquinazoline
CAS No.	125096-72-2
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	4-Chloro-8-bromoquinazoline; 8-Bromo-4-chloro-quinazoline; Quinazoline, 8-bromo-4-chloro-; 125096-72-2; 8-Br-4-Cl-quinazoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloroquinazoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.