Description

7-Amino-4,4-Dimethyl-3,4-Dihydroquinolin-2(1H)-One is a high-purity, functionalized quinolinone derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique fused-ring structure containing both amino and carbonyl functionalities, enabling its use in the creation of complex molecules with specific biological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its quinoline scaffold.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where its structural motif can contribute to specific modes of action.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in display and lighting technologies.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing advanced colorants and fluorescent markers with enhanced stability.
• Ligand Synthesis for Catalysis: Utilized to create complex nitrogen-containing ligands for transition metal catalysts used in asymmetric synthesis.
• Academic and Contract Research: A valuable reagent for methodological studies and the construction of compound libraries in medicinal chemistry programs.

Basic Information

Item	Details
Product Name	7-Amino-4,4-Dimethyl-3,4-Dihydroquinolin-2(1H)-One
CAS No.	125089-59-0
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	7-Amino-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-2-one; 4,4-Dimethyl-7-amino-3,4-dihydro-2(1H)-quinolinone; 2(1H)-Quinolinone, 7-amino-3,4-dihydro-4,4-dimethyl-; 7-Amino-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-2-one; 4,4-Dimethyl-7-amino-1,2,3,4-tetrahydroquinolin-2-one; ADQ; 7-Amino-4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our production of 7-Amino-4,4-Dimethyl-3,4-Dihydroquinolin-2(1H)-One adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Every lot is analyzed using validated methods including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.