Description

1-Oxa-5-Azaspiro[2.5]Octane-5-Carboxylic Acid, Methyl Ester is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique spirocyclic and oxazolidinone-like structure, which serves as a versatile precursor for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers with specific thermal or mechanical properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and ring-opening reactions.

Basic Information

Product Name	1-Oxa-5-Azaspiro[2.5]Octane-5-Carboxylic Acid, Methyl Ester
CAS No.	125033-43-4
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	Methyl 1-oxa-5-azaspiro[2.5]octane-5-carboxylate; 5-Methoxycarbonyl-1-oxa-5-azaspiro[2.5]octane; 1-Oxa-5-azaspiro[2.5]octane-5-carboxylic acid methyl ester; Spiro[oxirane-2,2'-1,3-oxazolidine]-5'-carboxylic acid, methyl ester; Oxazolidine spiro-oxirane carboxylate
EINECS	Contact for details

Quality Control

Our production of 1-Oxa-5-Azaspiro[2.5]Octane-5-Carboxylic Acid, Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.