Description

1-Oxa-5-Azaspiro[2.4]Heptane-5-Carboxylic Acid, Ethyl Ester is a high-value, specialized heterocyclic building block featuring a unique spirocyclic structure. This compound is critical for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of spirocyclic drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with potentially new modes of action.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Potential building block for advanced polymers and functional materials with specific thermal or optical properties.
• Academic & Contract Research: Employed in methodological studies and discovery chemistry within university laboratories and CROs (Contract Research Organizations).
• Fine Chemical Synthesis: Intermediate for the production of other complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	1-Oxa-5-Azaspiro[2.4]Heptane-5-Carboxylic Acid, Ethyl Ester
CAS No.	125033-33-2
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	Ethyl 1-Oxa-5-azaspiro[2.4]heptane-5-carboxylate; 5-Ethoxycarbonyl-1-oxa-5-azaspiro[2.4]heptane; 1-Oxa-5-azaspiro[2.4]heptane-5-carboxylic acid ethyl ester; Azaspiro[2.4]heptane carboxylic acid ethyl ester derivative; Spirocyclic oxazolidinone ester; CAS 125033-33-2
EINECS	Contact for details

Quality Control

Every batch of 1-Oxa-5-Azaspiro[2.4]Heptane-5-Carboxylic Acid, Ethyl Ester is produced and tested under strict quality management protocols to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP requirements for advanced pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.