Description

Formamide, n-[2-(Chloroacetyl)Phenyl]-n-Ethyl- (9Ci) is a specialized organic compound featuring a formamide core substituted with a chloroacetylphenyl group. This molecular architecture makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those with complex aromatic amide structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor in the development of specialized electron-transport or host materials for display technologies.
• Ligand and Catalyst Development: Employed in the preparation of novel chelating ligands or organocatalysts for asymmetric synthesis.
• Polymer Modification: Can be used to introduce functional amide and aromatic groups into polymer backbones for specialty materials.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and condensation reactions.

Basic Information

Product Name	Formamide, n-[2-(Chloroacetyl)Phenyl]-n-Ethyl- (9Ci)
CAS No.	124958-88-9
Molecular Formula	C11H12ClNO2
Molecular Weight	225.67 g/mol
Synonyms	N-Ethyl-N-[2-(chloroacetyl)phenyl]formamide; 2'-(Chloroacetyl)-N-ethylformanilide; N-[2-(Chloroacetyl)phenyl]-N-ethylformamide; 1-Ethyl-3-(2-chloroacetyl)-2,1-benzoxazol-4(1H)-one (tautomer); Formanilide, N-ethyl-2'-(chloroacetyl)-; 124958-88-9; (9CI) designation compound
EINECS	Contact for details

Quality Control

Our high-purity Formamide, n-[2-(Chloroacetyl)Phenyl]-n-Ethyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.