Description

7-(3-(3-Hydroxy-4-(4'-Iodophenoxy)-1-Butenyl)-7-Oxabicyclo(2.2.1)Heptan-2-Yl)-5-Heptenoic Acid is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural complexity and precise biological activity, making it essential for synthesizing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies focused on developing treatments for cardiovascular, ocular, and inflammatory conditions.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel prostaglandin-based drugs targeting intraocular pressure, pulmonary hypertension, and gastric cytoprotection.
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate prostanoid receptor (EP, FP, IP) binding and signaling pathways.
• Process Development: Serves as a key intermediate in scaling up the production of specialty active pharmaceutical ingredients (APIs) under current Good Manufacturing Practice (cGMP) conditions.
• Analytical Standard: Employed in method development and validation for quality control laboratories using HPLC, LC-MS, and other chromatographic techniques.
• Preclinical Studies: Utilized in animal model research to evaluate the efficacy and pharmacokinetics of new chemical entities before clinical trials.

Basic Information

Product Name	7-(3-(3-Hydroxy-4-(4'-Iodophenoxy)-1-Butenyl)-7-Oxabicyclo(2.2.1)Heptan-2-Yl)-5-Heptenoic Acid
CAS No.	124924-85-2
Molecular Formula	C22H27IO5
Molecular Weight	498.35 g/mol
Synonyms	9-Deoxy-9-methylene-16-phenoxy-17,18,19,20-tetranor-PGE2 iodo analog; Iodophenyl Prostaglandin E2 Derivative; 7-[3-(3-Hydroxy-4-(4-iodophenoxy)-1-butenyl)-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic Acid; 16-(4-Iodophenoxy)-17,18,19,20-tetranor-9-deoxy-9-methylene-PGE2; Prostaglandin Iodo Analog Intermediate; 124924-85-2; 7-(3-(3-Hydroxy-4-(4'-Iodophenoxy)-1-butenyl)-7-oxabicyclo[2.2.1]heptan-2-yl)-5-heptenoic Acid
EINECS	Contact for details

Quality Control

Our 7-(3-(3-Hydroxy-4-(4'-Iodophenoxy)-1-Butenyl)-7-Oxabicyclo(2.2.1)Heptan-2-Yl)-5-Heptenoic Acid is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results for assay, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. The product is sensitive to strong acids and organic solvents; ensure proper segregation in storage areas. For long-term stability, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.