Description

6-Bromo-2-Piperazin-1-Yl-Quinoline is a high-purity, advanced pharmaceutical intermediate characterized by its quinoline core functionalized with bromine and a piperazine moiety. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and receptor antagonists.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Building Block: Serves as a versatile scaffold for further functionalization via the bromine atom and the piperazine nitrogen.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays and target validation studies.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	6-Bromo-2-Piperazin-1-Yl-Quinoline
CAS No.	124782-95-2
Molecular Formula	C₁₃H₁₅BrN₄
Molecular Weight	307.19 g/mol
Synonyms	6-Bromo-2-(1-piperazinyl)quinoline; 2-(Piperazin-1-yl)-6-bromoquinoline; 6-Bromo-2-piperazinylquinoline; Quinoline, 6-bromo-2-(1-piperazinyl)-; 124782-95-2; 6-Bromo-2-(piperazin-1-yl)quinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Piperazin-1-Yl-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.