Description

Benzeneacetic Acid, -α-,4-Dimethyl-, (-α-S)- (9Ci) is a chiral, non-racemic organic compound of significant interest in advanced chemical synthesis. This high-purity, single-enantiomer building block is critical for ensuring the stereochemical integrity and efficacy of final products. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and complex chiral molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Asymmetric Synthesis: Employed as a crucial building block in stereoselective synthesis, including alkylation, conjugate addition, and cyclization reactions.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Fine Chemical Production: Integral to the manufacture of high-value specialty chemicals, agrochemicals, and flavors & fragrances requiring specific stereochemistry.
• Academic and Industrial Research: Serves as a standard or starting material in methodological studies and process chemistry optimization within R&D laboratories.

Basic Information

Product Name	Benzeneacetic Acid, -α-,4-Dimethyl-, (-α-S)- (9Ci)
CAS No.	124709-72-4
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(S)-2-(4-Methylphenyl)propanoic Acid; (S)-p-Methylhydratropic Acid; (S)-2-(p-Tolyl)propionic Acid; (αS)-α-Methyl-4-methylbenzeneacetic Acid; L-(-)-p-Methylhydratropic Acid; (S)-Naproxen Impurity; (S)-2-(4-Methylphenyl)propionic Acid
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, -α-,4-Dimethyl-, (-α-S)- (9Ci) is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.