Description

Benzeneacetic Acid, -α-,4-Dimethyl-, (-α-R)- (9Ci) CAS NO 124709-71-3 is a chiral, substituted phenylacetic acid derivative characterized by its specific stereochemistry at the alpha carbon. This compound matters as a high-value chiral building block, enabling the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereocenters into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of enantiopure drugs, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Material Science: Potential monomer or modifier in the synthesis of chiral polymers and advanced functional materials.

Basic Information

Product Name	Benzeneacetic Acid, -α-,4-Dimethyl-, (-α-R)- (9Ci)
CAS No.	124709-71-3
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(R)-2-(4-Methylphenyl)propanoic Acid; (R)-p-Methylhydratropic Acid; (R)-2-(p-Tolyl)propionic Acid; (R)-4-Methyl-α-methylbenzeneacetic Acid; (R)-2-(4-Methylphenyl)propionic Acid; (αR)-α,4-Dimethylbenzeneacetic Acid; (R)-Tolmetin Acid; (R)-MPPA
EINECS	Contact for details

Quality Control

Our chiral intermediates are produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing identity, purity (assay), enantiomeric excess (e.e.), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.