Description

1,4-Dioxaspiro[4.5]Decane-8-Acetonitrile CAS NO 124499-37-2 is a versatile spirocyclic nitrile compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique fused ring structure provides a rigid framework for constructing complex molecules, making it invaluable for research and development. This high-purity building block is essential for pharmaceutical chemists and agrochemical researchers developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its spirocyclic scaffold for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with specific thermal or optical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including ring-opening and functionalization reactions.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance compounds and other high-value specialty chemicals.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decane-8-Acetonitrile
CAS No.	124499-37-2
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	8-(Cyanomethyl)-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane-8-acetonitrile; Spiro[1,3-dioxolane-2,1'-cyclohexane]-8'-acetonitrile; 2-(1,4-Dioxaspiro[4.5]dec-8-yl)acetonitrile; 8-Acetonitrile-1,4-dioxaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Every batch of 1,4-Dioxaspiro[4.5]Decane-8-Acetonitrile is produced under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, GC, and NMR. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.