Description

2-(1,4-Dioxaspiro[4.5]Decan-8-Ylidene)Acetonitrile is a versatile spirocyclic nitrile building block, prized for its unique molecular architecture that enables the synthesis of complex, functionalized ring systems. This compound matters as a critical intermediate in advanced organic synthesis, offering a strategic handle for constructing pharmacologically active scaffolds and novel materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of spirocyclic compounds with potential biological activity, targeting central nervous system (CNS) and metabolic disease pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with spirocyclic motifs for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials requiring rigid, three-dimensional structures.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in cyclization and annulation reactions to form complex heterocycles.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	2-(1,4-Dioxaspiro[4.5]Decan-8-Ylidene)Acetonitrile
CAS No.	124499-35-0
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	8-(Cyanomethylene)-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane-8-acetonitrile, 8-ylidene-; 2-(1,4-Dioxaspiro[4.5]decan-8-ylidene)ethanenitrile; 8-(Cyanomethylene)-1,4-dioxaspiro[4.5]decane; Spiro[1,3-dioxolane-2,1'-cyclohexane]-8-acetonitrile, 8-ylidene-; (8-Methylene-1,4-dioxaspiro[4.5]decan-8-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(1,4-Dioxaspiro[4.5]Decan-8-Ylidene)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.