Description

2-(1,4-Dioxa-Spiro[4.5]Dec-8-Yl)-Ethylamine is a versatile spirocyclic amine derivative, a key building block in advanced organic synthesis. Its unique structure, featuring a protected ketone and a primary amine, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those requiring spirocyclic or heterocyclic frameworks for enhanced biological activity and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its amine functionality allows for the introduction of targeted bioactive groups.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, resins, and coatings with tailored properties.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	2-(1,4-Dioxa-Spiro[4.5]Dec-8-Yl)-Ethylamine
CAS No.	124499-34-9
Molecular Formula	C10H19NO2
Molecular Weight	185.26 g/mol
Synonyms	8-(2-Aminoethyl)-1,4-dioxaspiro[4.5]decane; 2-(1,4-Dioxaspiro[4.5]decan-8-yl)ethanamine; 1,4-Dioxaspiro[4.5]decane-8-ethylamine; 2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine; 8-(2-Aminoethyl)-1,4-dioxaspiro[4.5]decane; Spirocyclic Ethylamine Derivative
EINECS	Contact for details

Quality Control

Our 2-(1,4-Dioxa-Spiro[4.5]Dec-8-Yl)-Ethylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.