Description

Benzo(A)Pyrene-10-Sulfonic Acid, 7,8,9,10-Tetrahydro-7,8,9-Trihydroxy- , (7Alpha,8Beta,9Beta,10Alpha)-, (+-)- is a key sulfonated derivative of a polycyclic aromatic hydrocarbon (PAH) metabolite, offering a functionalized and water-soluble platform for advanced research and synthesis. This compound is of significant value for its role as a critical biochemical tool and synthetic intermediate in the study of carcinogenesis and metabolic pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers engaged in toxicology studies, biomarker development, and the synthesis of complex molecular probes.

Application

• Biochemical Research: Used as a standard, reference material, or intermediate in studies investigating the metabolic activation, DNA adduct formation, and carcinogenic mechanisms of Benzo(a)pyrene and related PAHs.
• Analytical Standard Development: Serves as a high-purity calibrant or internal standard for advanced analytical techniques like LC-MS/MS and HPLC in environmental and biological monitoring.
• Pharmaceutical R&D: Acts as a key synthetic building block or a molecular probe for developing inhibitors or modulators of enzymes involved in xenobiotic metabolism (e.g., cytochrome P450).
• Toxicology and Safety Assessment: Employed in in vitro and in vivo studies to understand metabolite toxicity and for the calibration of assays detecting PAH-derived biomarkers.
• Specialty Chemical Synthesis: Utilized as a functionalized intermediate for the preparation of more complex sulfonated derivatives, conjugates, or labeled compounds for diagnostic applications.

Basic Information

Item	Details
Product Name	Benzo(A)Pyrene-10-Sulfonic Acid, 7,8,9,10-Tetrahydro-7,8,9-Trihydroxy- , (7Alpha,8Beta,9Beta,10Alpha)-, (+-)-
CAS No.	124443-16-9
Molecular Formula	C20H16O6S
Molecular Weight	384.40 g/mol
Synonyms	(±)-7,8,9,10-Tetrahydro-7,8,9-trihydroxybenzo[a]pyrene-10-sulfonic acid; Benzo[a]pyrene-10-sulfonic acid, 7,8,9,10-tetrahydro-7,8,9-trihydroxy-, (7α,8β,9β,10α)-(±)-; BP-10-sulfonate, trihydro-tetrahydro derivative; 7,8,9-Trihydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene-10-sulfonic acid (racemic); A metabolite derivative of Benzo(a)pyrene sulfonate; PAH metabolite sulfonic acid
EINECS	Contact for details

Quality Control

Our Benzo(A)Pyrene-10-Sulfonic Acid derivative is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes rigorous analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The material is light-sensitive and should be handled under appropriate conditions to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0% (by titration or HPLC)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.