Description

1,4,8,11-Tetraazacyclotetradecane, Tetrahydrochloride is the tetrahydrochloride salt of a 14-membered tetraaza macrocyclic ligand, commonly known as cyclam. This compound is a crucial building block in coordination chemistry, valued for its strong and selective chelating properties towards transition metal ions. It is essential for researchers and manufacturers in pharmaceuticals, diagnostics, and advanced materials development who require a high-purity, reliable source of this versatile macrocyclic precursor.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of metal-based therapeutic agents and diagnostic imaging contrast media.
• Catalyst Synthesis: Used to create highly active and selective homogeneous catalysts for organic transformations and polymerization processes.
• Chemical Research: A fundamental reagent in academic and industrial R&D for studying metal-ligand interactions, supramolecular chemistry, and sensor development.
• Radiopharmaceuticals: Employed in the chelation of radioisotopes (e.g., Copper-64, Gallium-68) for positron emission tomography (PET) imaging and targeted radiotherapy.
• Waste Treatment: Functionalized derivatives can be used in the selective removal and recovery of heavy metal ions from industrial effluents.
• Material Science: Incorporated into the design of metal-organic frameworks (MOFs), molecular magnets, and other functional materials.

Basic Information

Product Name	1,4,8,11-Tetraazacyclotetradecane, Tetrahydrochloride
CAS No.	124346-03-8
Molecular Formula	C10H26N4·4HCl
Molecular Weight	359.18 g/mol (as tetrahydrochloride)
Synonyms	Cyclam Tetrahydrochloride; 1,4,8,11-Tetraazacyclotetradecane Tetrahydrochloride; 1,4,8,11-Tetraazacyclotetradecane Hydrochloride; Tetrahydrochloride Salt of Cyclam; 1,4,8,11-Tetraazacyclotetradecane, Hydrochloride (1:4); 1,4,8,11-Tetraazatetradecane Tetrahydrochloride; 1,4,8,11-Tetraazacyclotetradecane, 4HCl
EINECS	Contact for details

Quality Control

Our 1,4,8,11-Tetraazacyclotetradecane, Tetrahydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.