Description

4-Chloroquinazolin-2-Amine is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core quinazoline scaffold, functionalized with reactive chlorine and amine groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the quinazoline pharmacophore.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and functional polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to produce complex, high-value specialty chemicals.

Basic Information

Product Name	4-Chloroquinazolin-2-Amine
CAS No.	124309-74-6
Molecular Formula	C8H6ClN3
Molecular Weight	179.61 g/mol
Synonyms	2-Amino-4-chloroquinazoline; 4-Chloro-2-quinazolinamine; 4-Chloro-2-aminquinazoline; 4-Chloroquinazolin-2-ylamine; 2-Quinazolinamine, 4-chloro-; 4-Chloro-2-aminoquinazoline; 4-Chlor-2-aminochinazolin (German)
EINECS	Contact for details

Quality Control

Our 4-Chloroquinazolin-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.