Description

.Beta.-D-Ribo-Hexopyranose, 3-Deoxy-6-o-(1,1-Dimethylethyl)Dimethylsilyl-4-o-(Phenylmethyl)-2-o-2-Propenyl- is a sophisticated, multi-protected carbohydrate derivative that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in its precisely engineered structure, which provides selective reactivity for constructing complex molecules with high stereochemical fidelity. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for the development of nucleoside analogs, antiviral agents, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Glycochemistry Research: Advanced building block for the preparation of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Process Chemistry: Used in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs) requiring specific sugar modifications.
• Chemical Biology Probes: Enables the synthesis of labeled or modified sugars for studying biological recognition and metabolic pathways.
• Fine Chemical Synthesis: Intermediate for creating specialty chemicals, flavors, and fragrances that require complex carbohydrate scaffolds.
• Academic & R&D: A valuable tool for methodological development in synthetic organic chemistry and catalysis.

Basic Information

Product Name	.Beta.-D-Ribo-Hexopyranose, 3-Deoxy-6-o-(1,1-Dimethylethyl)Dimethylsilyl-4-o-(Phenylmethyl)-2-o-2-Propenyl-
CAS No.	123921-06-2
Molecular Formula	C22H36O5Si
Molecular Weight	408.61 g/mol
Synonyms	3-Deoxy-6-O-(tert-butyldimethylsilyl)-4-O-benzyl-2-O-allyl-β-D-ribo-hexopyranose; 2-O-Allyl-4-O-benzyl-3-deoxy-6-O-(tert-butyldimethylsilyl)-β-D-ribo-hexopyranose; 6-O-TBDMS-4-O-Bn-2-O-allyl-3-deoxy-β-D-ribo-hexopyranose; Protected 3-Deoxy-D-ribo-hexose derivative; TBDMS-protected benzyl allyl glycoside; CAS 123921-06-2
EINECS	Contact for details

Quality Control

Our production of this advanced synthetic intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for critical research and development. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.