Description

1,2,3,4-Tetrahydroquinoline-2-Carboxylic Acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its fused bicyclic structure, incorporating both a carboxylic acid and a tetrahydroquinoline moiety, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or building block for functional polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals and complex organic molecules for various industrial applications.

Basic Information

Product Name	1,2,3,4-Tetrahydroquinoline-2-Carboxylic Acid
CAS No.	123811-82-5
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	2-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-; Tetrahydroquinoline-2-carboxylic acid; 1,2,3,4-Tetrahydro-2-quinolinecarboxylic acid; 2-Carboxy-1,2,3,4-tetrahydroquinoline; (1,2,3,4-Tetrahydroquinolin-2-yl)carboxylic acid; THQ-2-COOH; 1,2,3,4-THQ-2-COOH
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroquinoline-2-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.