Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 4-Methyl-, Endo- (9Ci) is a high-purity, functionalized norbornene derivative characterized by its strained bicyclic structure and carboxylic acid group. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block for synthesizing complex molecules with tailored properties. It is essential for research and production in pharmaceutical development, agrochemicals, and specialty polymer chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used as a precursor for creating novel pesticides and herbicides with enhanced efficacy and selectivity.
• Specialty Polymer Monomer: Serves as a functional monomer in ring-opening metathesis polymerization (ROMP) and other polymerization techniques to produce polymers with unique thermal and mechanical properties.
• Material Science Research: Employed in the development of advanced materials, including liquid crystals, coatings, and adhesives.
• Organic Synthesis Building Block: Utilized in Diels-Alder reactions and other cycloadditions to construct complex polycyclic frameworks in medicinal and process chemistry.
• Catalyst Ligand Precursor: The carboxylic acid functionality allows for derivatization into ligands for asymmetric catalysis.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 4-Methyl-, Endo- (9Ci)
CAS No.	123639-98-5
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	4-Methylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid, endo-; endo-4-Methyl-5-norbornene-2-carboxylic acid; 4-Methyl-2-norbornene-5-carboxylic acid, endo-; 2-Norbornene-5-carboxylic acid, 4-methyl-, endo-; 4-Methyl-2,5-norbornadienecarboxylic acid (related); 4-Methyl-5-norbornene-endo-2-carboxylic Acid; 4-Methyl-endo-5-norbornene-2-carboxylic Acid; 4-Methylbicyclo[2.2.1]hept-5-ene-endo-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 4-Methyl-, Endo- (9Ci) adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and GC for residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Chiral Purity (HPLC)	≥ 99.0% ee (endo-isomer)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.