Description

2-Aziridinecarboxylicacid,1-[(Methylamino)Carbonyl]-,Methylester,(1R-Trans)-(9Ci) is a high-purity, stereochemically defined aziridine derivative, a versatile building block in advanced organic synthesis. Its value lies in its unique strained three-membered ring structure, which is highly reactive and serves as a key precursor for introducing functionalized amine moieties into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive aziridine ring for structure-activity optimization.
• Polymer Modification: Acts as a cross-linking agent or monomer for producing specialty polymers with tailored properties such as adhesion or chemical resistance.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation Chemistry: Employed in the functionalization of biomolecules for diagnostic and therapeutic applications.
• Academic and R&D: A valuable tool in organic chemistry research for studying ring-opening reactions and developing new synthetic methodologies.

Basic Information

Product Name	2-Aziridinecarboxylicacid,1-[(Methylamino)Carbonyl]-,Methylester,(1R-Trans)-(9Ci)
CAS No.	123620-70-2
Molecular Formula	C7H12N2O3
Molecular Weight	172.18 g/mol
Synonyms	(1R,2R)-1-(Methoxycarbonyl)-2-[(methylcarbamoyl)aziridine]; Methyl (1R,2R)-1-[(methylamino)carbonyl]aziridine-2-carboxylate; (1R,2R)-2-(Methoxycarbonyl)-1-(N-methylcarbamoyl)aziridine; trans-1-(Methoxycarbonyl)-2-(N-methylcarbamoyl)aziridine; (1R-trans)-1-[(Methylamino)carbonyl]aziridine-2-carboxylic acid methyl ester; Aziridine-2-carboxylic acid derivative, (1R,2R)-isomer
EINECS	Contact for details

Quality Control

Our 2-Aziridinecarboxylicacid,1-[(Methylamino)Carbonyl]-,Methylester,(1R-Trans)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and scale-up activities. We provide comprehensive analytical data, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.