Description

(R)-3-Aminoquinuclidine Dihydrochloride is a high-purity, enantiomerically pure chiral building block and pharmaceutical intermediate. This compound is of significant value for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of neurology and cardiology. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in asymmetric synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules targeting neurological receptors.
• Asymmetric Catalysis Research: Used as a precursor or ligand in the development of novel chiral catalysts.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	(R)-3-Aminoquinuclidine Dihydrochloride
CAS No.	123536-14-1
Molecular Formula	C7H14N2 · 2HCl
Molecular Weight	215.12 g/mol
Synonyms	(R)-3-Aminoquinuclidine Dihydrochloride; (3R)-3-Aminoquinuclidine Dihydrochloride; (R)-3-Aminoquinuclidinium Chloride; (R)-3-Aminoquinuclidine Hydrochloride; (R)-3-Amino-1-azabicyclo[2.2.2]octane Dihydrochloride; (R)-3-AQ Dihydrochloride; (R)-3-Aminotropane Dihydrochloride (related structure); (R)-3-Aminonortropane Dihydrochloride (related structure)
EINECS	Contact for details

Quality Control

Our (R)-3-Aminoquinuclidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.