Description

3-Aminophenylacetic Acid, n-Boc Protected is a key protected intermediate in organic synthesis, specifically designed for the controlled introduction of the 3-aminophenylacetic acid moiety. This compound is crucial for researchers and manufacturers requiring high-purity building blocks for complex molecule assembly, particularly in pharmaceutical development. It is primarily utilized by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Peptide Mimetics & Conjugate Synthesis: Used to incorporate phenylglycine-like structures into peptide backbones or to create drug-linker conjugates for targeted therapies and prodrugs.
• Agrochemical Research: Serves as a synthetic precursor for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes, enzyme inhibitors, and other tools for studying biological pathways.
• Material Science: Acts as a monomer or functionalization agent in the production of specialized polymers, dendrimers, and smart materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	3-Aminophenylacetic Acid, n-Boc Protected
CAS No.	123036-51-1
Molecular Formula	C₁₃H₁₇NO₄
Molecular Weight	251.28 g/mol
Synonyms	Boc-3-Aminophenylacetic Acid; 2-(3-((tert-Butoxycarbonyl)amino)phenyl)acetic Acid; N-Boc-3-Aminophenylacetic Acid; tert-Butyl (3-(carboxymethyl)phenyl)carbamate; 3-((tert-Butoxycarbonyl)amino)phenylacetic Acid; 2-[3-[(2-Methylpropan-2-yl)oxycarbonylamino]phenyl]acetic Acid; (3-((tert-Butoxycarbonyl)amino)phenyl)acetic Acid
EINECS	Contact for details

Quality Control

Our 3-Aminophenylacetic Acid, n-Boc Protected is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5% w/w
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.