Description

Ethyl 8-Hydroxyquinoline-3-Carboxylate is a versatile organic ester derivative of 8-hydroxyquinoline, a privileged scaffold in medicinal and industrial chemistry. This compound serves as a critical synthetic intermediate and functional material due to its chelating properties and structural motif. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting metal-associated diseases or possessing antimicrobial and anticancer activities.
• Agrochemical Synthesis: Used in the development of advanced fungicides and pesticides, leveraging the bioactivity of the 8-hydroxyquinoline core.
• Coordination Chemistry & Catalysis: Acts as a precursor for metal-chelating ligands used in homogeneous catalysis, material science, and analytical chemistry.
• Functional Material Development: Employed in the research and production of organic semiconductors, OLED materials, and sensors due to its electron-transport and luminescent properties.
• Analytical Reagent: Serves as a derivatization agent or a standard in chromatographic analysis for metal ion detection and quantification.
• Chemical Research: A valuable tool for organic synthesis, used in constructing complex heterocyclic compounds for various research applications.

Basic Information

Item	Details
Product Name	Ethyl 8-Hydroxyquinoline-3-Carboxylate
CAS No.	122855-37-2
Molecular Formula	C₁₂H₁₁NO₃
Molecular Weight	217.22 g/mol
Synonyms	Ethyl 8-Hydroxyquinaldine-3-carboxylate; 8-Hydroxyquinoline-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-8-hydroxyquinoline; Ethyl 3-Carboxy-8-hydroxyquinoline; 8-Hydroxy-3-quinolinecarboxylic Acid Ethyl Ester; 8-Hydroxyquinaldine-3-carboxylic Acid Ethyl Ester; Quinolin-8-ol, 3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 8-Hydroxyquinoline-3-Carboxylate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.