Description

2-Amino-3-Methylimidazo(4,5-F)-Quinoline 5-Sulfate Ester is a high-purity heterocyclic amine derivative of significant interest in advanced chemical research and development. This compound serves as a critical synthetic intermediate and reference standard for the study of mutagenic and carcinogenic compounds. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical developers engaged in toxicology, metabolic pathway analysis, and the synthesis of novel chemical entities.

Application

• Biochemical Research: Used as a reference standard and metabolite in studies investigating heterocyclic aromatic amines (HAAs) and their biological effects.
• Toxicology & Carcinogenicity Studies: Serves as a key analyte and model compound for understanding metabolic activation, DNA adduct formation, and mutagenicity mechanisms.
• Analytical Chemistry: Employed as a high-purity calibration standard in advanced chromatographic (HPLC, LC-MS) and spectroscopic methods for method development and validation.
• Pharmaceutical R&D: Acts as a sophisticated building block or intermediate in the synthesis of specialized compounds for pharmacological screening and discovery programs.
• Food Safety & Environmental Analysis: Utilized in the development of sensitive assays to detect and quantify mutagenic compounds in complex matrices like cooked foods and environmental samples.

Basic Information

Product Name	2-Amino-3-Methylimidazo(4,5-F)-Quinoline 5-Sulfate Ester
CAS No.	122719-40-8
Molecular Formula	C11H9N3O4S
Molecular Weight	279.27 g/mol
Synonyms	5-Sulfooxy-2-amino-3-methylimidazo[4,5-f]quinoline; 2-Amino-3-methylimidazo[4,5-f]quinolin-5-yl hydrogen sulfate; IQ-5-Sulfate; 2-Amino-3-methyl-3H-imidazo[4,5-f]quinolin-5-yl sulfate; 5-Hydrogen sulfate ester of IQ; 2-Amino-3-methylimidazoquinoline-5-sulfate; AMIQ-5-Sulfate; 122719-40-8
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Methylimidazo(4,5-F)-Quinoline 5-Sulfate Ester is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.