Description

1-Azabicyclo[2.2.1]Heptane-3-Carboxylic Acid, Methyl Ester is a specialized bicyclic amine ester building block of significant interest in advanced organic synthesis. This compound serves as a key chiral intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial chiral scaffold for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular drug discovery programs.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and functional materials.
• Academic and Industrial R&D: A valuable tool for methodological studies and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	1-Azabicyclo[2.2.1]Heptane-3-Carboxylic Acid, Methyl Ester
CAS No.	122684-38-2
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	Methyl 1-azabicyclo[2.2.1]heptane-3-carboxylate; 3-Carbomethoxy-1-azabicyclo[2.2.1]heptane; 1-Azabicyclo[2.2.1]heptane-3-carboxylic acid methyl ester; Methyl 3-azabicyclo[2.2.1]heptane-1-carboxylate (isomer); Endo-Methyl 1-azabicyclo[2.2.1]heptane-3-carboxylate; Exo-Methyl 1-azabicyclo[2.2.1]heptane-3-carboxylate; Bicyclic amine ester
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.1]Heptane-3-Carboxylic Acid, Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (endo/exo specified)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.