Description

2,4,6-Tris(Trifluoromethyl)Phenol is a highly fluorinated phenolic compound characterized by its unique trifluoromethyl substituents. This structure imparts significant electron-withdrawing properties, making it a valuable intermediate for advanced material synthesis. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel compounds with enhanced stability and performance.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, fungicides, and insecticides with higher efficacy and environmental selectivity.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, especially in cross-coupling and fluorination reactions.
• Advanced Material Precursor: Utilized in the production of specialty polymers, liquid crystals, and electronic materials where fluorine incorporation enhances thermal, chemical, and optical properties.
• Organic Synthesis Building Block: Acts as a versatile reagent for introducing the highly electron-deficient tris(trifluoromethyl)phenoxy group into complex molecular architectures.

Basic Information

Product Name	2,4,6-Tris(Trifluoromethyl)Phenol
CAS No.	122489-60-5
Molecular Formula	C9H3F9O
Molecular Weight	298.11 g/mol
Synonyms	2,4,6-Tris(trifluoromethyl)phenol; Phenol, 2,4,6-tris(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-3,5-bis(trifluoromethyl)phenol; 3,5-Bis(trifluoromethyl)-2-hydroxybenzotrifluoride; 2-Hydroxy-1,3,5-tris(trifluoromethyl)benzene; HTPB; TTMP
EINECS	Contact for details

Quality Control

Our 2,4,6-Tris(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali chemical properties, ensure it is stored separately from bases and other reactive substances.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	95 - 100 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.