Description

2'-Methoxy-5'-Nitrobenzamil is a specialized benzamil derivative, a chemical class known for its role as a sodium-calcium exchanger (NCX) inhibitor. This compound is significant for its utility in biochemical and pharmacological research, particularly in studies of ion transport mechanisms and cellular signaling pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel therapeutic agents or diagnostic tools.

Application

• Biochemical Research: Used as a potent and selective inhibitor of the sodium-calcium exchanger (NCX) in cellular and molecular biology studies.
• Pharmacological Studies: A key tool compound for investigating cardiac physiology, neuronal excitability, and other processes regulated by calcium ion flux.
• Pharmaceutical Intermediates: Serves as a critical building block or precursor in the synthesis of more complex molecules for drug discovery programs.
• Diagnostic Development: Potential use in the development of assays and kits for studying ion channel function and related disorders.
• Academic Research: Employed in university and institutional labs for fundamental research into cardiovascular and neurological diseases.

Basic Information

Product Name	2'-Methoxy-5'-Nitrobenzamil
CAS No.	122341-74-6
Molecular Formula	C15H15N3O4
Molecular Weight	301.30 g/mol
Synonyms	2'-Methoxy-5'-nitrobenzamil; 5'-Nitro-2'-methoxybenzamil; Benzamil, 2'-methoxy-5'-nitro-; NCX Inhibitor (2'-Methoxy-5'-Nitrobenzamil); 3',5-Diamino-6-chloro-N-(2-methoxy-5-nitrophenyl)pyrazine-2-carboxamide; (2-Methoxy-5-nitrophenyl)[(3,5-diamino-6-chloropyrazin-2-yl)carbonyl]azanide
EINECS	Contact for details

Quality Control

Our 2'-Methoxy-5'-Nitrobenzamil is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, minimize exposure during handling.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.