Description

1,5-Bis-Boc-1,5,9-Triazanonane is a high-purity, protected triamine derivative, primarily used as a sophisticated building block in organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecular architectures, particularly in pharmaceutical and advanced materials research. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex amine-containing active pharmaceutical ingredients (APIs), including kinase inhibitors and other targeted therapies.
• Peptidomimetic Synthesis: Used to introduce protected diamine or triamine spacers into peptide backbones, modifying stability and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating multidentate ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polyamides, polyurethanes, and epoxy resins with tailored properties.
• Chemical Linker: Utilized in bioconjugation and the development of antibody-drug conjugates (ADCs) due to its reactive amine sites and Boc-protection.
• Research & Development: A valuable tool for medicinal chemists in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.

Basic Information

Product Name	1,5-Bis-Boc-1,5,9-Triazanonane
CAS No.	122248-82-2
Molecular Formula	C₁₇H₃₅N₃O₄
Molecular Weight	345.48 g/mol
Synonyms	1,9-Bis(tert-butoxycarbonyl)-1,5,9-triazanonane; N1,N9-Bis-Boc-spermidine; 1,5-Bis(tert-butoxycarbonyl)-1,5,9-triazanonane; Spermidine, N1,N9-bis(tert-butoxycarbonyl)-; N1,N9-Di-Boc-spermidine; Boc-Spermidine-Boc; 1,5,9-Triazanonane, 1,5-bis[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl N-[5-[(tert-butoxycarbonyl)amino]pentyl]carbamate
EINECS	Contact for details

Quality Control

Our 1,5-Bis-Boc-1,5,9-Triazanonane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, from research to cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.