Description

cis-2-Amino-3-cyclopentene-1-carboxylic acid hydrochloride is a high-purity, non-proteinogenic amino acid derivative with a constrained cyclopentene ring structure. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering unique conformational control for drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including peptidomimetics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Peptidomimetics Development: Used to construct conformationally restricted peptide analogs to enhance metabolic stability and receptor selectivity.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chirality.
• Academic & Industrial R&D: Serves as a valuable reagent for method development and exploring new chemical spaces in organic chemistry.

Basic Information

Item	Detail
Product Name	cis-2-Amino-3-cyclopentene-1-carboxylic acid hydrochloride
CAS No.	122022-92-8
Molecular Formula	C6H10ClNO2
Molecular Weight	163.60 g/mol
Synonyms	(1R,2S)-2-Amino-3-cyclopentene-1-carboxylic acid hydrochloride; (1S,2R)-2-Amino-3-cyclopentene-1-carboxylic acid hydrochloride; cis-2-Aminocyclopent-3-ene-1-carboxylic acid hydrochloride; ACCA hydrochloride; 2-Amino-3-cyclopentene-1-carboxylic acid HCl; Cyclopentenylglycine hydrochloride (cis-); (1R,2S)-rel-2-Amino-3-cyclopentene-1-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our cis-2-Amino-3-cyclopentene-1-carboxylic acid hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.