Description

2-Bromo-Benzo-1,4-Dioxene is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its ability to introduce the benzo-1,4-dioxene moiety, a privileged structure found in various bioactive molecules and functional materials, through efficient cross-coupling and substitution reactions. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel compounds for drug discovery, crop protection, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular disorders where the benzo-1,4-dioxene scaffold is prevalent.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactivity to create complex bioactive molecules.
• Material Science & Organic Electronics: Serves as a building block for constructing π-conjugated systems and organic semiconductors used in OLEDs, OFETs, and sensors.
• Ligand & Catalyst Development: Employed to create novel chelating ligands for transition metal catalysts used in asymmetric synthesis and polymerization processes.
• Chemical Research & Development: A valuable reagent for methodological studies in organic chemistry, including palladium-catalyzed cross-couplings (Suzuki, Heck, Sonogashira) and nucleophilic aromatic substitutions.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the bromine atom allows for further functionalization and color tuning.

Basic Information

Product Name	2-Bromo-Benzo-1,4-Dioxene
CAS No.	121910-87-0
Molecular Formula	C8H7BrO2
Molecular Weight	215.04 g/mol
Synonyms	2-Bromo-1,4-benzodioxin; 2-Bromo-1,4-benzodioxane; 2-Bromobenzo-1,4-dioxane; 2-Bromo-2,3-dihydro-1,4-benzodioxin; 2-Bromo-1,4-benzodioxine; 2-Bromobenzo[d][1,3]dioxole (incorrect but common misnomer); Benzo-1,4-dioxene, 2-bromo-
EINECS	Contact for details

Quality Control

Our 2-Bromo-Benzo-1,4-Dioxene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.