Description

Ethyl-6,7-Difluoro-1,4-Dihydro-4-Oxo-3-Xynoline Carbonate is a high-purity, advanced pharmaceutical intermediate characterized by its specific fluorinated quinolone core structure. This compound is critical for the synthesis of novel, potent antibacterial agents, offering researchers and manufacturers a reliable building block for complex molecular development. It is primarily required by pharmaceutical R&D laboratories and active pharmaceutical ingredient (API) producers focused on next-generation fluoroquinolone antibiotics.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of new-generation fluoroquinolone antibiotic APIs.
• Antibacterial Drug Research: Used in medicinal chemistry for the design, synthesis, and structure-activity relationship (SAR) studies of novel antibacterial compounds.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for antibiotic manufacturing under cGMP conditions.
• Reference Standard: Utilized as an analytical standard for quality control and impurity profiling in API production.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) specializing in high-potency active pharmaceutical ingredients.

Basic Information

Product Name	Ethyl-6,7-Difluoro-1,4-Dihydro-4-Oxo-3-Xynoline Carbonate
CAS No.	121873-01-6
Molecular Formula	C₁₃H₉F₂NO₄
Molecular Weight	281.21 g/mol
Synonyms	Ethyl 6,7-Difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester; 6,7-Difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Ethyl 6,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 121873-01-6; Difluoroquinolone Ester Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl-6,7-Difluoro-1,4-Dihydro-4-Oxo-3-Xynoline Carbonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical synthesis. Production adheres to in-house specifications aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98% by HPLC), and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.