Description

2-(3-Aminopropyl)-1H-Isoindole-1,3(2H)-Dione, Hcl Salt is a high-purity organic compound, specifically a phthalimide derivative with a propylamine side chain, offered as its hydrochloride salt for enhanced stability and handling. This compound serves as a versatile and critical building block in advanced organic synthesis, enabling the development of complex molecular architectures. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological or oncological pathways.
• Peptide Mimetics & Conjugation: Used to introduce protected amine functionalities or as a linker/spacer in the design of peptide analogs and bioconjugates.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the synthesis of specialty polymers, such as polyimides or polymers with tailored surface properties.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, or plant growth regulators that require specific amine-based pharmacophores.
• Material Science Research: Serves as a precursor for creating functionalized surfaces, organic frameworks, or advanced materials with specific chemical reactivity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or cellular processes.

Basic Information

Product Name	2-(3-Aminopropyl)-1H-Isoindole-1,3(2H)-Dione, Hcl Salt
CAS No.	121821-01-0
Molecular Formula	C11H13N2O2 • HCl
Molecular Weight	240.69 g/mol (Free base: 203.23 g/mol)
Synonyms	N-(3-Aminopropyl)phthalimide hydrochloride; 3-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propylamine hydrochloride; 1,3-Dioxo-2-(3-aminopropyl)isoindoline hydrochloride; Phthalimidopropylamine hydrochloride; 2-(3-Aminopropyl)isoindoline-1,3-dione hydrochloride; N-Phthaloyl-1,3-diaminopropane hydrochloride; APPI-HCl; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-(3-Aminopropyl)-1H-Isoindole-1,3(2H)-Dione, Hcl Salt is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and production use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.