Description

Thiazolo[3,2-A]Benzimidazole, 8-Fluoro-2,3-Dihydro- (9Ci) is a specialized heterocyclic organic compound featuring a fused thiazole and benzimidazole core structure, substituted with a fluorine atom. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key scaffold for medicinal chemistry research, particularly in the development of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex, high-value compounds for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) with optimized biological activity.
• Fluorinated Compound Synthesis: The presence of the fluorine atom makes it a valuable precursor for introducing fluorinated motifs into molecules, a common strategy to enhance metabolic stability, bioavailability, and binding affinity.
• Heterocyclic Chemistry: Used in academic and industrial research focused on the synthesis and functionalization of complex fused heterocyclic systems.
• Agrochemical Research: Potential intermediate in the development of new generation pesticides and herbicides, leveraging the biological activity of the benzimidazole-thiazole framework.
• Material Science Precursor: Exploration into organic electronic materials, where such conjugated heterocycles can be used to tune electronic properties.

Basic Information

Product Name	Thiazolo[3,2-A]Benzimidazole, 8-Fluoro-2,3-Dihydro- (9Ci)
CAS No.	121712-06-9
Molecular Formula	C9H7FN2S
Molecular Weight	194.23 g/mol
Synonyms	8-Fluoro-2,3-dihydrothiazolo[3,2-a]benzimidazole; 8-Fluoro-2,3-dihydro-1H-thiazolo[3,2-a]benzimidazole; 8-Fluoro-2,3-dihydrothiazolo[3,2-a]benzimidazole (9CI); 8-Fluoro-2,3-dihydro[1,3]thiazolo[3,2-a]benzimidazole; Thiazolo[3,2-a]benzimidazole, 8-fluoro-2,3-dihydro-; 121712-06-9; 8-Fluoro-2,3-dihydro-1H-[1,3]thiazolo[3,2-a]benzimidazole
EINECS	Contact for details

Quality Control

Our production of Thiazolo[3,2-A]Benzimidazole, 8-Fluoro-2,3-Dihydro- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. All materials are subjected to comprehensive analytical testing including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.