Description

o-Fucopyranosyl-(1--3)-o-Galactopyranosyl-(1--4)-2-Acetamido-2-Deoxyglucopyranose (n-Acetyl-3'-o-Fucopyranosyllactosamine) is a complex, high-purity trisaccharide derivative that serves as a critical biochemical tool and synthetic intermediate. This compound is essential for research in glycobiology, enabling the study of carbohydrate-protein interactions, cell signaling, and the synthesis of more complex oligosaccharides. It is primarily utilized by pharmaceutical R&D teams, diagnostic developers, and academic researchers focused on immunology, cancer research, and infectious diseases.

Application

• Glycobiology Research: A fundamental substrate for studying fucosyltransferase and other glycosyltransferase enzyme activities and specificities.
• Pharmaceutical Development: Used as a key intermediate in the synthesis of complex oligosaccharides and glycoconjugates for novel therapeutic candidates, including vaccines and anti-inflammatory agents.
• Diagnostic Reagent Synthesis: Serves as a building block for producing glycan arrays, biosensors, and other diagnostic tools that detect specific antibodies or lectins.
• Cell Biology Studies: Employed to investigate cell surface recognition events, leukocyte trafficking, and host-pathogen interactions mediated by selectins and other glycan-binding proteins.
• Standards and Calibrants: Acts as a high-purity analytical standard for mass spectrometry (MS) and high-performance liquid chromatography (HPLC) in glycomics and metabolomics research.
• Enzyme Inhibition Studies: Useful in screening for and characterizing inhibitors of glycosidases and glycosyltransferases, which are targets for metabolic and infectious diseases.

Basic Information

Product Name	o-Fucopyranosyl-(1--3)-o-Galactopyranosyl-(1--4)-2-Acetamido-2-Deoxyglucopyranose (n-Acetyl-3'-o-Fucopyranosyllactosamine)
CAS No.	121686-59-7
Molecular Formula	C26H44N2O20
Molecular Weight	680.63 g/mol
Synonyms	3'-O-Fucosyllactosamine; N-Acetyl-3'-O-α-L-fucosyllactosamine; α-L-Fuc-(1→3)-β-D-Gal-(1→4)-D-GlcNAc; 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-3-O-α-L-fucopyranosyl-D-glucopyranose; Lacto-N-fucopentaose II precursor; Lewis a trisaccharide precursor; Blood group antigen precursor
EINECS	Contact for details

Quality Control

Every batch of our n-Acetyl-3'-o-Fucopyranosyllactosamine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and MS analyses. Our quality management system supports compliance with relevant research and development standards, ensuring material integrity for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.