Description

Methyl 4-(4'-Fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-based structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), where its specific substitution pattern is essential for imparting desired biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of oncology and anti-infective drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting specific enzyme pathways.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• API Synthesis: Serves as a core scaffold for constructing final Active Pharmaceutical Ingredients (APIs) with potential anti-cancer or antimicrobial properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	Methyl 4-(4'-Fluorophenyl)-2-(Cyclopropyl)-3-Quinolinecarboxylate
CAS No.	121659-86-7
Molecular Formula	C20H16FNO2
Molecular Weight	321.35 g/mol
Synonyms	Methyl 4-(4-fluorophenyl)-2-cyclopropylquinoline-3-carboxylate; 3-Quinolinecarboxylic acid, 4-(4-fluorophenyl)-2-cyclopropyl-, methyl ester; 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxylic acid methyl ester; 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic acid methyl ester; Methyl 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(4'-Fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.