Description

8-Chloroquinoline-4-Carboxylic Acid is a versatile halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, combining a reactive carboxylic acid group with a chlorinated quinoline core, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and photoactive compounds for electronic applications.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	8-Chloroquinoline-4-Carboxylic Acid
CAS No.	121490-66-2
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	4-Quinolinecarboxylic acid, 8-chloro-; 8-Chloro-4-quinolinecarboxylic acid; 8-Chloroquinaldin-4-carboxylic acid; 8-Chloro-4-quinolincarboxylic acid; 8-Chloroquinoline-4-carboxylate; 121490-66-2 (CAS); 8-Cl-QCA
EINECS	Contact for details

Quality Control

Our 8-Chloroquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.