Description

7-Oxabicyclo[4.1.0]Heptane, 4-Ethynyl-1-Methyl-, [1R-(1Alpha,4Alpha,6Alpha)]- (9Ci) is a high-purity, stereochemically defined oxirane derivative featuring a reactive ethynyl group. This compound is valued as a versatile chiral building block and advanced pharmaceutical intermediate for synthesizing complex molecules with high stereochemical fidelity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer & Material Science: The ethynyl and oxirane functionalities allow for incorporation into specialty polymers, resins, and cross-linked materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Fine Chemical Manufacturing: Employed in multi-step synthetic routes for producing high-value, complex organic compounds.

Basic Information

Item	Detail
Product Name	7-Oxabicyclo[4.1.0]Heptane, 4-Ethynyl-1-Methyl-, [1R-(1Alpha,4Alpha,6Alpha)]- (9Ci)
CAS No.	121467-29-6
Molecular Formula	C8H10O
Molecular Weight	122.16 g/mol
Synonyms	(1R,4R,6R)-4-Ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane; 4-Ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane, (1R,4R,6R)-; (-)-(1R,4R,6R)-4-Ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane; Chiral Oxirane Ethynyl Derivative; 7-Oxabicyclo[4.1.0]heptane, 4-ethynyl-1-methyl-, (1R,4R,6R)-; (1R,4R,6R)-1-Methyl-4-ethynyl-7-oxabicyclo[4.1.0]heptane
EINECS	Contact for details

Quality Control

Our 7-Oxabicyclo[4.1.0]Heptane, 4-Ethynyl-1-Methyl-, [1R-(1Alpha,4Alpha,6Alpha)]- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC and GC, to ensure compliance with exacting research and cGMP-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.