Description

n-Methylanatoxin is a synthetic analog of anatoxin-a, a potent neurotoxin originally isolated from cyanobacteria. This compound is of significant interest in neuroscience and pharmacology research as a highly selective and potent agonist for nicotinic acetylcholine receptors. It serves as a critical research tool for studying receptor function, neurotoxicity mechanisms, and for the development of potential therapeutic agents targeting neurological pathways. Researchers in pharmaceutical development, toxicology, and academic neuroscience rely on this high-purity reference standard.

Application

• Neuroscience Research: Used as a potent pharmacological tool to study the structure and function of nicotinic acetylcholine receptors (nAChRs) in the central and peripheral nervous systems.
• Toxicology Studies: Serves as a reference standard for investigating the mechanisms of cyanobacterial toxin action and for developing detection methods in environmental and food safety monitoring.
• Drug Discovery: Acts as a key molecular scaffold or a comparative agent in the research and development of novel therapeutics for neurological disorders, including Alzheimer's disease and nicotine addiction.
• Pharmacological Profiling: Employed in in vitro and in vivo assays to characterize receptor subtype selectivity, binding affinity, and downstream signaling pathways.
• Analytical Reference Standard: Provides a certified, high-purity standard for qualitative and quantitative analysis using techniques like HPLC, LC-MS, and NMR in analytical laboratories.

Basic Information

Item	Detail
Product Name	n-Methylanatoxin
CAS No.	120786-68-7
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	N-Methylanatoxin-a; (+)-N-Methylanatoxin A; 1-Methyl-9-azabicyclo[4.2.1]non-2-ene-2,3-epoxide; Anatoxin-a, N-methyl-; N-Methyl-anatoxin; Homoanatoxin; Fast Death Factor analog; N-Me-ANTX-a
EINECS	Contact for details

Quality Control

Our n-Methylanatoxin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS) for identity confirmation, and NMR spectroscopy. A detailed Certificate of Analysis (COA) documenting identity, purity, and analytical data is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation. Keep the container in a dry, well-ventilated area and handle with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.