Description

Huperzine A is a potent, naturally occurring alkaloid and a highly selective, reversible acetylcholinesterase (AChE) inhibitor. This compound is of significant interest for its neuroprotective properties and its role in modulating cholinergic function. It is primarily utilized in the pharmaceutical and nutraceutical industries for research and development into cognitive support and neurological health applications.

Application

• Pharmaceutical Intermediates: Serves as a key active pharmaceutical ingredient (API) or intermediate in the formulation of prescription and over-the-counter cognitive enhancers.
• Dietary Supplements & Nutraceuticals: Incorporated into nootropic and brain health supplements aimed at supporting memory, focus, and cognitive function.
• Neurological Research: A critical reference standard and tool compound in preclinical and clinical research focused on Alzheimer's disease, dementia, and other neurodegenerative conditions.
• Biochemical Studies: Used in enzymatic assays to study acetylcholinesterase inhibition kinetics and mechanism of action.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, and other chromatographic methods.

Basic Information

Product Name	Huperzine A
CAS No.	120786-18-7
Molecular Formula	C15H18N2O
Molecular Weight	242.32 g/mol
Synonyms	(-)-Huperzine A; Huperzine-A; Selagine; 5-Amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one; (5R,9R,11E)-5-Amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one; L-Huperzine A; Neurotrophic Alkaloid
EINECS	Contact for details

Quality Control

Our Huperzine A is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and MS, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.