Description

1,2-Dithiane-4,5-Diol, 1,1-Dioxide, trans- is a specialized chiral sulfone derivative, serving as a high-value synthetic intermediate and ligand in asymmetric catalysis. Its unique structure, featuring a rigid dithiane dioxide backbone with vicinal diol functionality, makes it a critical building block for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require enantiomerically pure intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research.
• Asymmetric Catalysis: Utilized as a chiral ligand or auxiliary in transition metal-catalyzed reactions to induce high enantioselectivity.
• Agrochemical Synthesis: Intermediate in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Precursor for functionalized polymers and liquid crystals where specific molecular geometry is required.
• Organic Synthesis Research: Valuable reagent for academic and industrial R&D in developing new stereoselective methodologies.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of chiral aroma chemicals.

Basic Information

Product Name	1,2-Dithiane-4,5-Diol, 1,1-Dioxide, trans-
CAS No.	120586-50-7
Molecular Formula	C4H8O4S2
Molecular Weight	184.23 g/mol
Synonyms	trans-1,2-Dithiane-4,5-diol 1,1-dioxide; (4R,5R)-1,2-Dithiane-4,5-diol 1,1-dioxide; (4S,5S)-1,2-Dithiane-4,5-diol 1,1-dioxide; (R,R)-1,2-Dithiane-4,5-diol 1,1-dioxide; (S,S)-1,2-Dithiane-4,5-diol 1,1-dioxide; Dithiane Dioxide Diol; Chiral Dithiane Dioxide; 4,5-Dihydroxy-1,2-dithiane 1,1-dioxide
EINECS	Contact for details

Quality Control

Our 1,2-Dithiane-4,5-Diol, 1,1-Dioxide, trans- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Specified range provided on COA
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.