Description

(S)-o-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl]-Hydroxyamine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its role as a key precursor for the introduction of the hydroxyamine functional group in a stereocontrolled manner, enabling the production of complex molecules with defined chirality. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, particularly in the development of enzyme inhibitors and receptor modulators.
• Asymmetric Synthesis: Used in stereoselective reactions to construct molecules with specific three-dimensional configurations, crucial for drug efficacy and safety.
• Agrochemical Research: Serves as a building block for creating novel, chiral pesticides and herbicides with improved selectivity and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for transition metal catalysis, enhancing reaction efficiency and selectivity.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances where precise stereochemistry is required.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the discovery of new synthetic pathways.

Basic Information

Product Name	(S)-o-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl]-Hydroxyamine Hydrochloride
CAS No.	120564-14-9
Molecular Formula	C7H16ClNO3
Molecular Weight	197.66 g/mol
Synonyms	(S)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanamine, N-hydroxy-, hydrochloride; (S)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanamine, N-hydroxy-, hydrochloride; (S)-O-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl]hydroxylamine hydrochloride; (S)-4-(Aminomethyl)-2,2-dimethyl-1,3-dioxolane N-oxide hydrochloride; (S)-Isopropylidene glyceraldehyde oxime hydrochloride; Chiral hydroxyamine hydrochloride derivative; (S)-Dioxolane hydroxyamine HCl
EINECS	Contact for details

Quality Control

Our (S)-o-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl]-Hydroxyamine Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.